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Of interest to the subject discussed in this paper, fermented foods have also been studied in other inflammatory conditions and, although more research is needed, results suggested that these foods can exert beneficial effects in conditions characterized by chronic inflammation

Notwithstanding about the promising mechanisms of action, translation to patients is limited by bioavailability and pharmacokinetic issues, inter-subject variability and possible interactions with other chemotherapeutic agents or endocrine therapies highlighting the need for well-conducted randomised controlled trials and PKPD studies (248)

Medication enters (injection), distributes evenly throughout (absorption), and leaves at a rate determined by the half-life (elimination)

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